Stimulate Change is an exciting new treatment serum from Osmosis for photodamage. It has retinaldehyde liposome which is proven in published research to be equal to Retin A in strength but without the irritation. It also uses high levels of niacinamide, growth factors, copper peptides, matrixyl, alpha lipoic acid…all in an enhanced liposomal formula. The best way to improve the skin is by maintaining the health of the barrier and this formula does that by stimulating change in the skin rather than over-exfoliating and irritating the skin. For more information please circle reader reply 255